#6738 ALCOHOL LOCK IN CRBSI: A PANACEA

Abstract Background and Aims CRBSI is a dreaded complication of permcath, with reported incidence 1.1 – 5.5 episodes/1000 days. Many these patients especially those infected Staphylococcus aureus, Pseudomonas aeruginosa or fungal growth require catheter removal. 70% alcohol possibly breaks the biofilm in exposes hidden bacteria to antibiotics. This study was done find usefulness lock established CRBSI. Method All dialysis our centre permcath as vascular access were subjects study. given heparin after each session. diagnosed per CDC/IDSA criteria. addition antibiotics also (2 ml port) for 3 consecutive Outcome term clinical response need removal studied. The outcome this group compared (retrospective controls) who only not lock. Results Over last two years 166 permcaths placed institution. Eighty nine them continued centre. Their total follow up period 12028 days (30-720 days). There 18 episodes 14 (1.5 1000 Three (16.67%) required removal, rest all improved 150 (30 -420 days), have been doing well there has no episode leak break block. On comparing retrospective control 22 CRBSI, lock, 15 (68.18%) (P = 0.001). Conclusion present though on small numbers, shows that works boon setting It avoids majority patients.